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    Links to other sites are provided as a convenience to the viewer. Pfizer accepts no responsibility for the content of linked sites. This website is neither owned nor controlled by Pfizer. Pfizer does not endorse and is not responsible for the content or services of this site. Continue You are now leaving to enter a website neither owned nor operated by Pfizer. Links to all outside sites are provided as a resource to our visitors and do not imply an endorsement or recommendation of a particular physician by Pfizer, nor an endorsement of any Pfizer product by a telehealth provider or any physician. Pfizer accepts no responsibility or liability for the content or services of other websites. fluconazole warfarin The medication, originally developed with the intention to treat high blood pressure in adults, became a hit for males struggling in the bedroom and the New York-based drugmaker when it was introduced to the U. An estimated 1 in 10 men are affected by erectile dysfunction, or ED, according to the Cleveland Clinic. In its first quarter, Viagra brought a total of $400 million in revenue for Pfizer and would later produce annual sales of about $1.8 billion. Viagra was the first noninvasive treatment for male impotency and opened up a previously undiscussed dialogue between men and their doctors about sexual health. Nearly 21 years later, sales of the brand-name drug have dropped. sales of "the little blue pill" declined 73 percent year over year in 2018 from $789 million to $217 million, Pfizer said in its fourth-quarter earnings report, as generics entered the market. Pfizer lost exclusive rights to the drug in December 2017, bringing with it a flood of generic versions. Despite generic competition from other drugmakers, Pfizer has been able to maintain a significant market share thanks, in part, to launching its own generic version of the blue, diamond-shaped pill. In late 2017, Pfizer announced it would produce a generic version, called sildenafil, at half the cost of the brand name. The company also said at the time it would offer new discount programs and increase its copayment card discounts to make the brand version more accessible to patients. Thirty percent of prescriptions were for rival Cialis and its generic, tadalafil.

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    These highlights do not include all the information needed to use VIAGRA safely and effectively. VIAGRA® (sildenafil citrate) tablets, for oral use Initial U. Approval: 1998 For most patients, the recommended dose is 50 mg taken, as needed, approximately 1 hour before sexual activity. However, VIAGRA may be taken anywhere from 30 minutes to 4 hours before sexual activity. The maximum recommended dosing frequency is once per day. Based on effectiveness and toleration, the dose may be increased to a maximum recommended dose of 100 mg or decreased to 25 mg. VIAGRA was shown to potentiate the hypotensive effects of nitrates and its administration in patients who use nitric oxide donors such as organic nitrates or organic nitrites in any form is therefore contraindicated [ The recommended dose for ritonavir-treated patients is 25 mg prior to sexual activity and the recommended maximum dose is 25 mg within a 48 hour period because concomitant administration increased the blood levels of sildenafil by 11-fold [ Consider a starting dose of 25 mg in patients treated with strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole, or saquinavir) or erythromycin. Clinical data have shown that co-administration with saquinavir or erythromycin increased plasma levels of sildenafil by about 3 fold [ VIAGRA is supplied as blue, film-coated, rounded-diamond-shaped tablets containing sildenafil citrate equivalent to 25 mg, 50 mg, or 100 mg of sildenafil. Tablets are debossed with PFIZER on one side and VGR25, VGR50 or VGR100 on the other to indicate the dosage strengths. Men with erectile dysfunction (ED) can now buy Viagra online directly from Pfizer, the drug’s manufacturer. Pfizer has partnered with CVS/pharmacy to launch Viagra.com, which allows patients to purchase the drug online from a trusted source, said the company in a recent news release. By providing this safe and legitimate alternative for buying Viagra, Pfizer hopes to rein in the sale of counterfeit products from fake online pharmacies that prey on unsuspecting patients. In 2011, the company evaluated 22 websites appearing in the top search results for the phrase “buy Viagra” and conducted chemical analysis of the drugs advertised as Viagra. Pfizer found that 80% percent of the drugs were counterfeit and contained only 30% to 50% of sildenafil citrate, Viagra’s active ingredient. In addition to containing the wrong active ingredient or incorrect amounts of that ingredient, counterfeits are often “manufactured in filthy and deplorable conditions” and may include “potentially dangerous contaminants” said Matthew Bassiur, Vice President of Pfizer Global Security, in the news release. “Samples of counterfeit Viagra tested by our labs have contained pesticides, wallboard, commercial paint, and printer ink,” Bassiur continued. Fake online pharmacies and the products they sell are an escalating public health threat.

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