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Prednisone liver disease

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    Prednisone liver disease


    Regardless of which type of autoimmune hepatitis you have, the goal of treatment is to slow or stop the immune system attack on your liver. To meet this goal, you'll need medications that lower immune system activity. A second medication, azathioprine (Azasan, Imuran), may be recommended in addition to prednisone. Prednisone, especially when taken long term, can cause a wide range of serious side effects, including diabetes, thinning bones (osteoporosis), broken bones (osteonecrosis), high blood pressure, cataracts, glaucoma and weight gain. Doctors typically prescribe prednisone at a high dose for about the first month of treatment. Then, to reduce the risk of side effects, they gradually reduce the dose over the next several months until reaching the lowest possible dose that controls the disease. Adding azathioprine also helps you avoid prednisone side effects. Most people need to continue taking the prednisone for at least 18 to 24 months, and many remain on it for life. Although you may experience remission a few years after starting treatment, the disease often returns if the drug is discontinued. should i buy generic propecia Autoimmune hepatitis (AIH) is a chronic inflammatory condition of the liver of unknown etiology identified in the 1940s and formerly called chronic active hepatitis. Autoimmune hepatitis is characterized by liver transaminase elevation in the presence of autoantibodies, elevated gamma globulin levels, interface hepatitis on histology, and a great response to corticosteroids. Back to Top Autoimmune hepatitis occurs worldwide but the exact incidence and prevalence of the disease in the United States is unknown. The point prevalence and incidence of AIH in Northern Europeans is approximately 18 per 100,000 people per year and 1.1 per 100,000 people per year, respectively, and it is assumed that this data can be extrapolated to the North American population. Interestingly the prevalence of AIH in Native Alaskan population is much higher, with a point prevalence of 42 per 100,000 people/year. However AIH occurs in both genders and in all age groups and there have been reports of newly diagnosed AIH in patients 80 years of age. Autoimmune hepatitis is subdivided in 2 types, according to the pattern of autoantibodies.

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    Prednisone is a synthetic corticosteroid that reduces inflammation and suppresses the immune system. Prednisone is prescribed for a wide range of conditions, especially autoimmune diseases. sertraline antidepressant Prising chronic active liver disease CALDinclude three recent controlled trials with steroids, azathio-prine, or both. Cook and associates 1971showed that variable doses ofprednisolone from 10 to 2.5 mgdaily improved certain liver function tests and survival. Therapy with prednisone 15 mgdaily was foundbyMurray-Lyon andhis colleagues. Cutaneous manifestations of chronic liver disease and other autoimmune diseases such asPrednisone and prednisolone are equally effective. An acceptable regimen is prednisone or.

    Fatty liver is a nonpermanent, or reversible, condition involving the accumulation of triglycerides -- a fat molecule -- inside cells of the liver by a process called steatosis. As fats accumulate in the cell, they displace vital cell structures and eventually distort the shape of the nucleus. According to the California Pacific Medical Center, the use of prednisone -- a steroid medication -- may result in the development of fatty liver. Alcoholic and nonalcoholic comprise the two main types of fatty liver. This differentiation between alcoholic and nonalcoholic is rather appropriate, since alcohol is a major cause of fatty liver and other causes are less frequent. Regardless of cause, biopsy of the liver -- a process of acquiring a liver tissue sample -- reveals largely similar architectural deformities in the liver, but with slight differences unique to alcohol. Prednisone has many side effects, some more serious than others. Regardless, when experiencing side effects likely related to prednisone, notify a physician as soon as possible. This site does not dispense medical advice or advice of any kind. Site users seeking medical advice about their specific situation should consult with their own physician. Click In order for us to create your customized Health Savvy programs, we need a little more information about the health topic(s) that you are interested in. Press "Continue" button below to begin selecting your Health Savvy topic(s). Remember, you need at least one selected topic to use Health Savvy. If you choose this option, it cannot be undone, and you'll need to choose at least new topic to continue using your Health Savvy programs. Are you still sure that you want to clear all of you selected topics?

    Prednisone liver disease

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    Prednisone is inactive in the body and, in order to be effective, first must be converted to prednisolone by enzymes in the liver. Therefore, prednisone may not work as effectively in people with liver disease whose ability to convert prednisone to prednisolone is impaired. The FDA approved prednisone in 1955. buy prednisone 20mg uk Prednisone Sterapred is a prescription corticosteroid, a man-made form of steroids that the body normally produces to fight illnesses and injuries. Prednisone Warnings and Precautions Prior to taking prednisone, let your healthcare provider know if you have diabetes, liver disease, or high blood pressure, among other conditions. You should not take prednisone if you have a systemic fungal infection or are allergic to any components of the drug.

     
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