Prednisolone is indicated in the management of all conditions deemed likely to benefit from short or long term glucocorticoid therapy. These include: Allergic states Severe, incapacitating allergies unresponsive to conventional treatment; asthma serum sickness; drug hypersensitivity reactions. Collagen disorders Eg systemic lupus erythematosus, polymyositis, polymyalgia rheumatica and temporal (giant cell) arteritis, mixed connective tissue disease syndrome, acute rheumatic carditis. Rheumatic disorders Usually given as an adjunctive therapy for short term administration during an acute episode or exacerbation of rheumatoid arthritis, psoriatic arthritis. Skin conditions Life-threatening or incapacitating skin conditions such as pemphigus and exfoliative dermatitis. Neoplastic disease Leukaemias and lymphomas in adults, acute leukaemia of childhood. Gastro-Intestinal disease During acute exacerbation in ulcerative colitis and regional ileitis (Crohn's Disease). trazodone buy canada Prednisolone is one of a group of medicines known as steroids; specifically, it is a glucocorticosteroid. Glucocorticosteroids occur naturally in the body, helping to maintain good body functioning and the health. Prednisolone is effective in the treatment of many different inflammatory diseases and conditions. Such diseases include autoimmune diseases (e.g., rheumatoid arthritis, systemic lupus erythematosus, and ulcerative colitis), and skin, blood, respiratory, kidney, bowel, muscle, and joint problems. If left untreated, the inflammation may escalate and worsen your condition. By taking extra glucocorticoids, Prednisolone acts by reducing inflammation. Prednisolone is often taken in a tablet, which comes in a range of doses and in regular, gastro-resistant, and soluble forms. 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