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    After consolidation of the antidepressive response, it is recommended to continue treatment for several months, in order to avoid relapse. Therapeutic response is usually seen after 2-4 weeks of treatment. However, there is no clinical evidence suggesting that patients not responding to the initial recommended dose may benefit from dose up-titrations. Dosages above 60 mg once daily, up to a maximum dose of 120 mg per day have been evaluated from a safety perspective in clinical trials. Major Depressive Disorder: The starting and recommended maintenance dose is 60 mg once daily with or without food. In patients responding to duloxetine, and with a history of repeated episodes of major depression, further long-term treatment at a dose of 60 to 120 mg/day could be considered. Generalised Anxiety Disorder: The recommended starting dose in patients with generalised anxiety disorder is 30 mg once daily with or without food. clomid erectile dysfunction Enter the shape, color, or imprint of your prescription or OTC drug. Our pill identification tool will display pictures that you can compare to your pill. Get Started Comment: I suffer from osteoarthritis and major depressive disorder. Show Full Comment Comment: I suffer from osteoarthritis and major depressive disorder. After 11years on paxil, and having read the possible benefit of pain reduction, I asked doctor about changing. After 11years on paxil, and having read the possible benefit of pain reduction, I asked doctor about changing. I don't think there is any difference in pain control, but I hate to think how bad it would be without it. I stepped down from Paxil, while starting duloxetine on small dose then increasing as Paxil was phased out. I stepped down from Paxil, while starting duloxetine on small dose then increasing as Paxil was phased out. I believe my body had become immune to or adjusted to the Paxil so much that it was no longer effective. Other than some sweating at night, I have no side effects. I am a content person now and no longer dread social situations.

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    Coversyl Brand Name Coversyl Common Name perindopril In this drug factsheet How does this medication work? What will it do for me? How should I use this medication? inderal overdose symptoms Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0. 4. Dirks AC, van Hyfte DM "Recurrent hyponatremia after substitution of citalopram with duloxetine." J Clin Psychopharmacol 27 2007 313. 5. Kruger S, Lindstaedt M "Duloxetine and hyponatremia a report of 5 cases." J Clin Psychopharmacol 27 2007 101-104. 6. Among Duloxetine-Treated Patients in Placebo-Controlled. 17.1 Information on Medication Guide Trials. 17.2 Clinical Worsening and Suicide Risk 6.5 Adverse Reactions Occurring at an Incidence of 2% or More. 17.3 Medication Administration Among Duloxetine-Treated Patients in Placebo-Controlled. 17.4 Continuing the Therapy Prescribed Trials

    Commonly reported side effects of duloxetine include: asthenia, constipation, diarrhea, dizziness, drowsiness, fatigue, hypersomnia, insomnia, nausea, sedated state, headache, and xerostomia. Other side effects include: agitation, erectile dysfunction, nervousness, psychomotor agitation, tension, vomiting, abdominal pain, anorexia, decreased appetite, decreased libido, hyperhidrosis, loss of libido, and restlessness. See below for a comprehensive list of adverse effects. Applies to duloxetine: oral capsule delayed release Along with its needed effects, duloxetine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking duloxetine: Some side effects of duloxetine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Duloxetine was approved for the treatment of major depression in 2004. While duloxetine has demonstrated improvement in depression-related symptoms compared to placebo, comparisons of duloxetine to other antidepressant medications have been less successful. A 2012 Cochrane Review did not find greater efficacy of duloxetine compared to SSRIs and newer antidepressants. Additionally, the review found evidence that duloxetine has increased side effects and reduced tolerability compared to other antidepressants. It thus did not recommend duloxetine as a first line treatment for major depressive disorder, given the (then) high cost of duloxetine compared to inexpensive off-patent antidepressants and lack of increased efficacy. do not list duloxetine among the recommended treatment options. A review from the Annals of Internal Medicine lists duloxetine among the first line drug treatments, however, along with citalopram, escitalopram, sertraline, paroxetine, and venlafaxine.

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