Moa of chloroquine in malaria

Discussion in 'Online Canadian Pharmacy' started by Deemik, 10-Mar-2020.

  1. senior User

    Moa of chloroquine in malaria


    Malaria parasites can enter the body through these mosquito bites, and then live in body tissues such as red blood cells or the liver. This medication is used to kill the malaria parasites living inside red blood cells.

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    Chloroquine, brand name Aralen, is an anti-malarial drug. It is similar to hydroxychloroquine Plaquenil, and is useful in treating several forms of malaria as well as amebiasis that has spread outside of the intestines. Approved indication For acute attacks of malaria due to P vivax, P malariae, P ovale, and susceptible strains of P falciparum CDC Recommendations Chloroquine-sensitive uncomplicated malaria Plasmodium species or species not identified 600 mg base 1 g salt orally at once, followed by 300 mg base 500 mg salt. Chloroquine is an antimalarial. It is used to prevent malaria and it is also used as a treatment for acute malaria. Chloroquine by itself is not recommended anymore due to the widespread resistance to it. Therefore, chloroquine is now used in combination with proguanil for travel to certain countries.

    Both drugs may be needed for a complete cure and to prevent the return of infection (relapse). In some cases, you may need to take a different medication (such as primaquine) to kill the malaria parasites living in other body tissues.

    Moa of chloroquine in malaria

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  6. The clinical usefulness of chloroquine, and in some recent cases of quinine as well, has been much reduced by the evolution and spread of chloroquine resistant malaria parasites. The mechanism of resistance involves a reduced accumulation of the drug, although again the mechanism involved is controversial.

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    For treatment of acute attacks of malaria in adults, one dose is usually taken right away, followed by half the dose 6 to 8 hours later and then half the dose once a day for the next 2 days. For prevention and treatment of malaria in infants and children, the amount of chloroquine phosphate is based on the child's weight. Resistance to chloroquine of malaria strains is known to be associated with a parasite protein named PfCRT, the mutated form of which is able to reduce chloroquine accumulation in the digestive vacuole of the pathogen. Chloroquine is the generic form of the brand-name prescription medicine Aralen, which is used to prevent and treat malaria — a mosquito-borne disease caused by a parasite — and to treat.

     
  7. the Andrey User

    Hydroxychloroquine is a quinoline medicine used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. The use of diazepam in chloroquine poisoning - RAJAH - 1990. Chloroquine poisoning • LITFL • Clinical Case Tox Conundrum Drugs & Medications That Can Trigger Psoriasis Flare-Ups
     
  8. Snurik User

    Hydroxychloroquine is a quinoline medicine used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria Common and Rare Side Effects for Plaquenil Oral A case of thrombocytopenia associated with the use of.
     
  9. VladCa New Member

    Ask the Expert Plaquenil and Sjögren’s The rash typically occurs in the first 6 weeks and is usually mild. In general, the rash will resolve within 2 weeks after stopping the drug. A more severe rash affecting larger areas of the body may occur but is not common. If this type of rash occurs, other medications such as anti-histamines and steroids may be required to help with symptoms.

    Adverse Cutaneous Reactions to Hydroxychloroquine Are More.
     
  10. TiMe Well-Known Member

    Hydroxychloroquine-Induced Cardiomyopathy Circulation. Mar 01, 2011 New clinical and ultrastructural findings in hydroxychloroquine-induced cardiomyopathy a report of 2 cases. The American Heart Association is qualified 501c3.

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