Malaria parasites can enter the body through these mosquito bites, and then live in body tissues such as red blood cells or the liver. This medication is used to kill the malaria parasites living inside red blood cells. Specific test for the retina when going on plaquenil Hydroxychloroquine missed dose Effects of plaquenil in pregnancy Chloroquine, brand name Aralen, is an anti-malarial drug. It is similar to hydroxychloroquine Plaquenil, and is useful in treating several forms of malaria as well as amebiasis that has spread outside of the intestines. Approved indication For acute attacks of malaria due to P vivax, P malariae, P ovale, and susceptible strains of P falciparum CDC Recommendations Chloroquine-sensitive uncomplicated malaria Plasmodium species or species not identified 600 mg base 1 g salt orally at once, followed by 300 mg base 500 mg salt. Chloroquine is an antimalarial. It is used to prevent malaria and it is also used as a treatment for acute malaria. Chloroquine by itself is not recommended anymore due to the widespread resistance to it. Therefore, chloroquine is now used in combination with proguanil for travel to certain countries. Both drugs may be needed for a complete cure and to prevent the return of infection (relapse). In some cases, you may need to take a different medication (such as primaquine) to kill the malaria parasites living in other body tissues. Moa of chloroquine in malaria Chloroquine confirmed as anti-viral drug for Coronavirus, Chloroquine Dosage Guide with Precautions - Plaquenil allergic reaction rashWhat is hydroxychloroquine 200 mg used forCan hydroxy chloroquine affect birth controlUsual doseagefor plaquenil The clinical usefulness of chloroquine, and in some recent cases of quinine as well, has been much reduced by the evolution and spread of chloroquine resistant malaria parasites. The mechanism of resistance involves a reduced accumulation of the drug, although again the mechanism involved is controversial. Chloroquine mechanism of drug action and resistance in.. Chloroquine and Proguanil - Superdrug Health Clinic. Chloroquine Mode of Action Science. For treatment of acute attacks of malaria in adults, one dose is usually taken right away, followed by half the dose 6 to 8 hours later and then half the dose once a day for the next 2 days. For prevention and treatment of malaria in infants and children, the amount of chloroquine phosphate is based on the child's weight. Resistance to chloroquine of malaria strains is known to be associated with a parasite protein named PfCRT, the mutated form of which is able to reduce chloroquine accumulation in the digestive vacuole of the pathogen. Chloroquine is the generic form of the brand-name prescription medicine Aralen, which is used to prevent and treat malaria — a mosquito-borne disease caused by a parasite — and to treat.