Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Plaquenil toxicity Chloroquine phosphate in pregnancy Since hydroxychloroquine may increase the effects of antidiabetic drugs or insulin, a decrease in the doses of these drugs may be required while taking hydroxychloroquine. In literature, cases of human pregnancy while taking hydroxychloroquine have occurred and no increase in the rate of birth defects has been noted. Hydroxychloroquine HCQ has been shown to improve survival rates in other inflammatory diseases. We aimed to assess the available literature on the cardiovascular impact of HCQ in patients with RA. METHODS We systematically searched for studies evaluating the effects of HCQ on cardiovascular outcomes of known risk factors for CVD in patients with RA. For months now my skin has been thickening I have now reached the point where I feel as though my arms are going to split like a sausage and been extremely inflamed and painful. A month ago I started on Plaquenil and prednisolone. It has helped a bit with the inflammation but on reading various. Hydroxychloroquine may also be used for purposes not listed in this medication guide. Hydroxychloroquine is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Benefits of hydroxychloroquine Metabolic and cardiovascular benefits of hydroxychloroquine., Metabolic and cardiovascular benefits of. Methotrexate plaquenil sulfasalazine Research into the wide-ranging effects of hydroxychloroquine has revealed many important benefits in the treatment of lupus; it must be noted that these benefits may be less effective in people who smoke Arthritis Care & Research 2010; 3–400. Benefits include Decrease in the number of disease flares. Drug spotlight on hydroxychloroquine Lupus Foundation of.. Plaquenil pros and cons - Sclero Forums MAIN - Sclero Forums. Hydroxychloroquine MedlinePlus Drug Information. Plaquenil hydroxychloroquine is an antimalarial medication used to treat or prevent malaria, a disease caused by parasites, which enter the body through the bite of a mosquito. Plaquenil is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. And, smoking is not recommended for anyone, particularly those with a higher risk of cardiovascular disease. To prevent upset stomach, take Plaquenil with food. Also, the generic version of Plaquenil, hydroxychloroquine, can cause additional stomach irritation. If you are experiencing consistent stomach aches. Combining telbivudine Tyzeka and hydroxychloroquine may increase the risk of unexplained muscle pain, tenderness, or weakness because both drugs cause such side effects. Hydroxychloroquine suppresses the immune system and should not be combined with drugs that also suppress the immune system or live vaccines.