Keep in mind that most people with Sjogren's stay healthy and don't have serious problems. You should be able to keep doing all the things you love to do without making many changes. Chloroquine drug bank Chloroquine-medicated salt Hydroxychloroquine mode of action Hydroxychloroquine is safe, even for pregnant women with Sjogren’s syndrome. Rarely, it can accumulate in the retina, the tissue at the back of the eye that helps to create images to be processed by the brain. Deposits on the retina can lead to vision changes. About half of the time, Sjogren’s occurs with Rheumatoid Arthritis or other rheumatoid diseases; this is Secondary Sjogren’s. However, Sjogren’s can appear alone; then it is Primary Sjogren’s. Sjogren’s incidence is about 90% female. What will I notice with Sjogren’s syndrome? Patients may not be aware that their tear ducts are less. Aug 14, 2017 Plaquenil is the brand name of hydroxychloroquine, a drug used to prevent or treat malaria 2. Plaquenil is also used for long-term treatment of autoimmune diseases such as rheumatoid arthritis RA and systemic lupus erythmatosis. According to the Mayo Clinic, it can take up to six months' constant use before an effect is seen in RA 1. Plaquenil can cause serious side effects when used in high doses for chronic diseases such as RA over the long term. Conditions like this are called autoimmune diseases. Sjogren's causes your immune system to go haywire and attack healthy cells instead of invading bacteria or viruses. Does plaquenil reduce rheumatoid factor in patiences with sjogrens PATIENT FACT SHEET Sjögren’s Syndrome, What is Sjogren's Syndrome? Rheumatoid Arthritis Warrior Hydroxychloroquine blood monitoringChloroquine dose in rheumatoid arthritisWoman in grey hydroxychloroquine-induced hyperpigmentationIncreased gas plaquenilBuy hydroxychloroquine sulfate online Summary. Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria. Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis.. Treating Lupus with Anti-Malarial Drugs Johns Hopkins.. A B cell activation results in hypergammaglobulinemia with elevated levels of circulating immune complexes and production of autoantibodies. Among the autoantibodies seen are rheumatoid factors RF, anti-Ro/SSA and anti-La/SSB 1 – 4. RF is found in the serum and saliva of 60–80% of pSS patients 5, 6. Plaquenil is effective for Lupus patients, as well as people with UCTD described to me by a rheumatologist as "Lupus-like" or "Lupus-lite" or "mild Lupus". So it's very possible to be on Plaquenil without having a formal Lupus diagnosis. To get a Lupus diganosis you need to have 4 or more of 11 Lupus criteria, within a 5 year period. Sjogren's Syndrome Support Group. Sjogren's syndrome is an autoimmune disorder in which immune cells attack and destroy the exocrine glands that produce tears and saliva. It also associated with rheumatic disorders such as rheumatoid arthritis, and it is rheumatoid factor positive in 90 percent of cases.