Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Plaquenil optometry exam Plaquenil dosing instructions Plaquenil and heart disease Aug 26, 2016 In summary Plaquenil isn't causing tyour new problems. It probably caused only the nausea, diarrhea, stomach cramps, and intense vertigo. BTW 100 mg daily may reduce side effects, but this low dosage also greatly annihilates its positive effects. 100 mg are a drop maybe two. on a hot stone Abdominal pain is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 5 - 10 years, also take medication Enbrel, and have Pain. I've gradually have become sensitive to dairy but the last few days, it all but kills me. I've been on Plaquenil for almost 2 wks now and I'm also taking Prednisone, could one of these be causing my extreme stomach cramps? 2 nights ago, I had a cheeseburger and mac and cheese and I thought I was going to die about 1 in the morning. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. This medicine is not effective against all strains of malaria. Cramps and plaquenil Stomach cramps from Plaquenil - what to do? Lupus Forums at., Will you have Abdominal pain with Plaquenil - eHealthMe Taking 4mg plaquenilPlaquenil and melatonin I started taking Plaquenil 4 weeks ago for non specific autoimmune disease as indicated by ANA. Symptoms were low grade temperature off and on for a year, joint pain and fatigue. I have already felt some relief. Some nauseau at first but less problem with fever and joint pain. But, now I have started having stomach cramps and diarrhea. I understand these may go away. Is there anything I can. Stomach problems with Plaquenil • Johns Hopkins Arthritis Center. Plaquenil and stomach issues." Lupus Community - Support.. How Lupus Affects the Muscles, Tendons and Joints Lupus.. I've been on Plaquenil for almost 2 wks now and I'm also taking Prednisone, could one of these be causing my extreme stomach cramps? 2 nights ago, I had a cheeseburger and mac and cheese and I thought I was going to die about 1 in the morning. I ended up throwing up once and then I had diarrhea for a bit and then it passed once my system cleared. QUOTE=DawnI have been on plaquenil for around 8 months or so but these leg cramps have just gotten worse and the ladies I work with told me to get calcium with magnesium. That would help out with the leg cramps but I am worried with all the meds that I take I am afraid that it might interact with the meds. I've been taking Plaquenil 400 mg for nearly 6 mos. I didn't seem to have any problems whatsoever with it initially, other than very short term and mild cramping/diarrhea. But now I've been dealing with considerable muscle aching and pain/spasm in some new places - or at least places that haven't bothered me in quite awhile.