Since I have not taken it my chest feels so much better which is odd because chest pain is not listed as a side effect. Also I noticed that the Plaquenil I think was making me feel different but not in a good way. Plaquenil related cardiomyopathy Hydroxychloroquine normal dose Plaquenil is a slow-acting drug, meaning that it can take up to 6 months to experience the full benefits of this medication, but it is possible for symptoms to improve in as few as 1 or 2 months. Plaquenil and other antimalarials are the key to controlling lupus long-term, and some lupus patients may be on Plaquenil for the rest of their lives. Taking Plaquenil long-term or at high doses may cause irreversible damage to the retina of your eye. Stop taking Plaquenil and call your doctor at once if you have trouble focusing, if you see light streaks or flashes in your vision, or if you notice any swelling or color changes in your eyes. Mar 24, 2011 What next if plaquenil doesn't work. Really though in order not to have worse things happen it is what we have to do. I know it is scary but anything to stop the. Did you take yourself off Plaquenil, or did your doctor tell you to go off it? Plus I will be honest the whole eye site thing even though rare has always freaked me out. I went off of it to see if I can manage not being on it as my lupus isnt as severe as other cases but already I am feeling very fatigued and my legs feel heavy if that makes sense. I can discuss alternatives with my DR at my next appt but my DR feels as though the plaq is the best bet for my level of illness. If so are you just dealing with Lupus symptoms or did you take another med? I'm on Plaquenil, and after the first week's GI upset, I have had no problems with it. What happens if you stop plaquenil Plaquenil - Side Effects, Uses, Dosage, Overdose, Pregnancy, Alcohol., Plaquenil Uses, Dosage & Side Effects - Dosage of chloroquine syrup for childrenPlaquenil and chest painMaleria medicine and other uses plaquenilPlaquenil and face rashChloroquine hydrochloride dose Hydroxychloroquine is a DMARD. The brand name is Plaquenil. What to do if you forget to take your Plaquenil. If you miss a dose of Plaquenil, do not make it up or double your next dose. If you must stop it, it will take a while for the side effects to go away. You should have an eye examination every year to prevent a very rare but. Lupus Medicines Hydroxychloroquine - Brigham and Women's.. What next if plaquenil doesn't work?. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. Plaquenil is supposed to stay in your system for 1-2 months after you stop taking it. Try to rest, stay hydrated and away from sick ppl for now and hopefully you will not have any issues Jun 13, 2019 What happens if retinal damage is found? If your ophthalmologist finds any signs of retinal damage, he or she will tell your primary care doctor or inflammatory disease specialist to stop Plaquenil treatment immediately. This will help you avoid permanent vision loss. Your other doctor will find another treatment for your disease. If you have a tolerance for methadone and just suddenly stop taking it, you will begin to experience withdrawals such as nausea, body aches, hot and cold sweats, and diarrhea.