These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Plaquenil and plastic surgery Plaquenil hair loss Plaquenil can cause serious side effects when used in high doses for chronic diseases such as RA over the long term. The New Zealand Dermatological Society recommends that to decrease the risk of retina damage, no more than 200mg of Plaquenil should be taken a day, and a dose of 400mg per day should be taken no longer than a few weeks. Get emergency medical help if you have signs of an allergic reaction hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Check with your doctor immediately if any of the following side effects occur Incidence not known. Blistering, peeling, loosening of the skin blurred vision or other vision changes chest discomfort, pain, or tightness cough or hoarseness dark urine decreased urination defective color vision diarrhea difficulty breathing If you notice any other effects, check with your healthcare professional. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Other side effects not listed may also occur in some patients. Plaquenil 200mg side effects Plaquenil Side Effects Common, Severe, Long Term -, Plaquenil Hydroxychloroquine Side effects, Images, Uses. Chloroquine for malaria prophylaxis dosingPlaquenil and pregnancyPlaquenil and ldnChloroquine phosphate reef tank Hydroxychloroquine Plaquenil and sulfasalazine Azulfidine are used for mild rheumatoid arthritis. They are not as powerful as other DMARDs, but they usually cause fewer side effects. In rare cases, Plaquenil can adversely affect the eyes, and people taking this medicine should be seen by an ophthalmologist at least once a year. What are the side effects of using hydroxychloroquine.. Hydroxychloroquine Oral Route Side Effects - Mayo Clinic. Common Plaquenil side effects a study from FDA data - eHealthMe. Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. When cut, too much of the drug can be released at once and cause a reaction or side effects. When prescribed 300 mg. daily, you should alternate one tablet one day with two the next. I've been on Plaquenil for almost four years now and it's helped me a lot. What are the side effects of hydroxychloroquine Plaquenil? Side effects include irritability, headache, weakness, hair lightening or loss, stomach upset, nausea, dizziness, muscle pain, rash and itching.