It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Tinnitus and hydroxychloroquine Germany plaquenil About 25% of patients receiving chloroquine or hydroxychloroquine for several years develop bluish-grey pigmentation on face, neck and sometimes lower legs and forearms Continuous long-term use may lead to blue-black patches, especially in sun-exposed areas Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. I've been on Plaquenil about 2 months, and it has helped my knee/back pain, which is wonderful. Instead of brown spots, I get solid dark brown arms, but I have little spots on my arms with NO pigment, so there are white polka dots. I get these now on my arms and legs and I'm not on Plaquenil. Plaquenil and skin discoloration. SMF 2.0. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Hydroxychloroquine skin darkening Hydroxychloroquine Oral Route Side Effects - Mayo Clinic, Hydroxychloroquine Plaquenil Mechanism of action of chloroquine in malariaRecommended eye for sjogrens plaquenilIs there an interaction between tindamax and plaquenil Hydroxychloroquine. What is Hydroxychloroquine? Hydroxychloroquine is an anti-malarial drug that is used to treat a wide variety of skin conditions. The way in which it works is unknown but it is understood to have anti-inflammatory effects. What is Hydroxychloroquine used for? ACD A-Z of Skin - Hydroxychloroquine. Plaquenil and skin discoloration - Sjogren's World. Hydroxychloroquine-Induced Pigmentation in Patients With.. Hydroxychloroquine is one of several antimalarial drugs that have anti-inflammatory effects useful in other diseases. It is licensed in the UK for the treatment of malaria. Hydroxychloroquine is particularly effective for systemic lupus erythematosus SLE and discoid lupus erythematosus DLE. I have no idea if this is like what is happening to you, but when I first went on plaquenil I got some weird pigment changes on my forehead some darkening that has ended up being permanent. My rheumy said that plaquenil can make you even more sun sensitive, so it looks like some sun exposure along with the plaq caused my pigment changes. Indigestion, diarrhoea, headache, blurred vision, darkening of the skin, or bleaching of the hair. Hydroxychloroquine can aggravate pre-existing psoriasis. Does hydroxychloroquine affect fertility or pregnancy? Hydroxychloroquine must be avoided during pregnancy as it may harm the unborn child.