Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Aralen malaria prophylaxis Hydroxychloroquine plaquenil american college of rheumatology More energy on plaquenil Plaquenil qt prolongation Glutathione Whitening Pills - 2000mg Glutathione - Better than Skin Lightening Cream - Dark Spots & Acne Scar Remover, Hyperpigmentation Treatment - Anti-aging Effect and Powerful Antioxidant - 60caps Beauty The other exciting is tranexamic acid is also coming in a topical form. You should be able to get some cosmeceutical products with topical tranexamic acid, which is really exciting. That’s something that’s going to be very helpful in treating hyperpigmentation and melasma. It’s also important to mention that we’re now seeing glutathione. Hydroxychloroquine Plaquenil is not a new therapy. It has been used in rheumatology for decades and it's proven a very useful medication. I think it's due to Hydroxycholoroquine-induced hyperpigmentation an example of drug-induced skin pigmentation. I thought it worth showing those of you on the medication. Why is it so much worse on. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Glutathione plaquenil hyperpigmentation Hydroxychloroquine-Induced Pigmentation in Patients With Systemic Lupus., New treatments and approaches in melasma Dermatology Times Plaquenil guidelines aao 2016 Note This document contains side effect information about hydroxychloroquine. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Plaquenil Side Effects Common, Severe, Long Term -. Plaquenil Pigmentation - BJC Health. Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects.. Glutathione is a powerful antioxidant that your body makes as a defense against the oxidative stresses of everyday life. Although the oral supplemental form is generally considered safe for many conditions, some glutathione side effects can result with its improper use. How does Glutathione for Hyperpigmentation work? Glutathione injections at Clinicbe Skin of Colour contain an anti-ageing blend which works to regulate the production of melanin. Since overproduction of melanin is the primary cause of hyperpigmentation, glutathione is very effective at treating skin discolouration and hyperpigmentation. We report two cases of hydroxychloroquine‐induced hyperpigmentation presenting in a 50‐year‐old Caucasian female case 1 and a 78‐year‐old female case 2, both receiving 400 mg per day. Case 1 had an arthritis predominant undifferentiated connective tissue disease, which was treated with hydroxychloroquine for 4–5 years.