Is plaquenil safe for pregnancy

Discussion in 'Chloroquine Drug' started by Android87, 13-Mar-2020.

  1. InforM User

    Is plaquenil safe for pregnancy


    The association between HCQ use and pregnancy outcomes (early spontaneous abortion, fetal death, and preterm and term live birth) was analyzed using generalized estimating equations (GEE) accounting for the occurrence of multiple pregnancies per patient. Analyses were adjusted for antiphospholipid antibody (a PL) status. 110 pregnancies (63 mostly Caucasian patients) were included, of which, in 30, HCQ was used; overall occurrence of flares was low (non-HCQ group: 5 mild (6.4%) and 2 severe (2.6%); HCQ group: 2 mild (6.7%) and no severe flares).

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    In brief Not safe. "usage of this drug during pregnancy should be avoided except when in the judgment of the physician the benefit outweighs the possible hazard. Please take note that this medication can rapidly be adsorbed by the placenta and my cause damage to the fetus's eyes. Hydroxychloroquine oral tablet is available as a brand-name drug and a generic drug. Brand name Plaquenil. Hydroxychloroquine comes only as a tablet you take by mouth. Hydroxychloroquine is used to treat malaria, lupus erythematosus, and rheumatoid arthritis. Technically, Plaquenil does not have an official pregnancy Category rating, as is common with older medications. However, most sources consider it to be a pregnancy Category C medication. In animal studies, it was shown that Plaquenil crosses the placenta and accumulates in the eyes of.

    Apart from disease flares during pregnancy, SLE patients have an increased risk of intrauterine growth restriction (OR 2.6), (pre)eclampsia (OR 3.0), and preterm birth (OR 2.4) compared to the healthy population [1]. The HCQ group showed a trend towards lower dosage of prednisone (OR 0.2 (95% CI 0.0–1.4); Pregnancy constitutes a challenge in patients with systemic lupus erythematosus (SLE).

    Is plaquenil safe for pregnancy

    PLAQUENIL®, Hydroxychloroquine Side Effects, Dosage, Uses, and More

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  6. HCQ drug level during pregnancy is likely to be even more unpredictable given the increased volume of distribution of the drug and the increase in the body mass index of pregnant women. Nonetheless, the evaluation of HCQ level during pregnancy could provide valuable information for disease management.

    • Too Little of a Good Thing Hydroxychloroquine in Pregnancy.
    • Plaquenil and Pregnancy - Antibiotics Home Page.
    • Hydroxychloroquine Use in Lupus Patients during Pregnancy..

    DüSSELDORF, GERMANY — The anti-inflammatory compound hydroxychloroquine appears to be relatively safe during pregnancy, according to a small number of studies totaling about 250 patients. But these studies have not provided overwhelming evidence proving the safety of this agent in pregnancy. Hydroxychloroquine Pregnancy Warnings Animal studies have revealed evidence of fetal harm. Use of chloroquine and other 4-aminoquinolines in high doses and for prolonged durations has been associated with neurological disturbances and interference with hearing, balance, and vision in the fetus. Generally considered safe. The following medications are viewed as relatively safe in pregnancy Hydroxychloroquine HCQ Sulfasalazine SSZ Low-dose aspirin Pregnancy – HCQ can be continued during ›

     
  7. Inetwm.RU Well-Known Member

    The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. PLAQUENIL Patient Assistance Program Plaquenil Hydroxychloroquine - Side Effects, Dosage. PLAQUENIL Dosage & Rx Info Uses, Side Effects
     
  8. technomaster Well-Known Member

    Plaquenil (hydroxychloroquine) belongs to a group of medicines called quinolines. The effect of hydroxychloroquine on glucose control and insulin. Plaquenil Uses, Dosage & Side Effects - Does intake of Plaquenil cause an increase in blood sugar levels.
     
  9. pio New Member

    Plaquenil Uses, Dosage & Side Effects - Plaquenil hydroxychloroquine belongs to a group of medicines called quinolines. Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia.

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