Hydroxychloroquine is available as the brand-name drug Plaquenil. Generic drugs usually cost less than the brand-name version. Hydroxychloroquine may be used as part of a combination therapy. Plaquenil and ipl Chloroquine as antiinflammatory Plaquenil helps fatigue Chloroquine life cycle Substitutes and alternatives to Plaquenil hydroxychloroquine for uses like Rheumatoid arthritis, Lupus and Malaria Plaquenil hydroxychloroquine Alternatives & Similar Drugs - Skip to full site navigation Hello! Here is a short list Prednisone, Imuran, Remicade, Methotrexate Later sidesteps Prednisone's side effects, which include weight gain, mood swings, diabetes and eye problems, such as cataracts. I hope this was helpful enough. The alternative to Plaquenil is a slightly different anti malarial called Quinacrine. Plaquenil replaced Quinacrine formerly called Atabrine for anti malarial prophylaxis so now the Quinacrine has to be made up into pills or gel capsules by a compounding pharmacy. Hydroxychloroquine is used to treat lupus erythematosus and rheumatoid arthritis. It isn’t fully understood how this drug works to treat lupus erythematosus or rheumatoid arthritis. That means you may need to take it with other drugs. It treats malaria by killing the parasites that cause the disease. Plaquenil substitute Hydroxychloroquine - Wikipedia, Alternatives to plaquenil Anti-Inflammatories. Long term use hydroxychloroquineDid plaquenil work for youChloroquine for lupus Is there a drug that I can take to replace plaquenil? Asked by tanner01. there are several drugs now that you can take instead of the plaquenil. these type of drugs they have now work in a different way then the methotrexate and plaquenil. most of these drugs you will still take the methotrexate. i researched these drugs before i. Is there a drug that I can take to replace plaquenil?. Discontinued Plaquenil.other options?. Hydroxychloroquine Plaquenil. Plaquenil hydroxychloroquine is commonly used to help keep mild lupus-related problems, such as skin and joint disease, under control. This drug is also effective at preventing lupus flares. Rheumatoid arthritis is a chronic disorder for which there is no known cure. Fortunately in the last few years, a shift in strategy toward the earlier institution of disease modifying drugs and the availability of new classes of medications have greatly improved the outcomes that can be expected by most patients. Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as.