Pattern of Retinopathy: Although the locus of toxic damage is parafoveal in many eyes, Asian patients often show an extramacular pattern of damage. Dose: We recommend a maximum daily HCQ use of 5.0 mg/kg real weight, which correlates better with risk than ideal weight. Plaquenil eye check Chloroquine fansidar and mefloquine Rheumatologists know hydroxychloroquine HCQ as the single most useful agent for lupus, and ophthalmologists know HCQ as a preventable cause of retinopathy that can result in blindness. And it was ophthalmologists, not rheumatologists, who published the latest guidelines limiting HCQ to no more than 5mg/kg a day. Higher doses can sometimes be used, but only in adults and not for all cases. Some people tolerate this medication much better than other people, so it is important that individuals who are considering taking hydroxychloroquine talk with their doctor about the lowest necessary dose to reduce or eliminate their symptoms. SARCOIDOSIS TREATMENT GUIDELINES INTRODUCTION Sarcoidosis is a chronic inflammatory granulomatous dis-ease that primarily affects the lungs, although multi-organ involvement is common. The etiology of sarcoidosis is not clear; however, genetic and environmental factors probably play a role in the development and expression of the disease. Risk of Toxicity: The risk of toxicity is dependent on daily dose and duration of use. There are no similar demographic data for CQ, but dose comparisons in older literature suggest using 2.3 mg/kg real weight. Plaquenil dosing guidelines Protecting your eyesight when taking Plaquenil Lupus., RA and Hydroxychloroquine How Effective is it for Rheumatoid Arthritis. Chloroquine genericChloroquine us brand nameDoxycycline plaquenilMeds for lupus plaquenil generic nameChloroquine class of drug Hydroxychloroquine comes in an oral tablet. Adult dosing ranges from 200 mg or 400 mg per day 6.5mg/kg. In some cases, higher doses can be used. It is recommended one tablet twice daily if taking more than one tablet. It is recommended to be taken with food. Hydroxychloroquine Plaquenil. SARCOIDOSIS TREATMENT GUIDELINES. Hydroxychloroquine Side Effects, Dosage, Uses, and More. Published April 20, 2011 New Plaquenil Guidelines Here is a look at the 2011 testing guidelines for patients on Plaquenil guidelines. Diana L. Shechtman, O. D. and Paul M. Karpecki, O. D. Detailed Hydroxychloroquine dosage information for adults and children. Includes dosages for Rheumatoid Arthritis, Systemic Lupus Erythematosus, Malaria Prophylaxis and more; plus renal, liver and dialysis adjustments. Dosage greater than 5.0mg/kg over five years dramatically increases the risk of retinal toxicity, and high doses can be exceedingly dangerous. As opposed to the 2011 guidelines, “real weight” is now considered a better indicator than “ideal weight” for calculating dosage for most patients.