Her rheumatologist instructed her to undergo a baseline ocular examination prior to initiating Plaquenil (hydroxychloroquine, Sanofi-Aventis) therapy. Toxic maculopathy associated with chloroquine use was first documented in the literature five decades ago.1 In the United States, Plaquenil––an analog to chloroquine––is used to treat a variety of conditions, including rheumatoid arthritis, lupus and several distinct inflammatory disorders. Although the incidence of macular toxicity is infrequent with Plaquenil use (at a dosage of 200mg or 400mg q.d.), its visual impact can be devastating. Can you breastfeed while on plaquenil Hydroxychloroquine sulphate brand name Chloroquine sle dose Most rheumatologists recommend patients undergo a baseline eye examination prior to starting Plaquenil and be re-examined in the future depending on their risk for developing the condition. Risk factors include advanced age and having pre-existing retinal disease. Jun 29, 2010 A baseline eye exam is a comprehensive eye exam that gives the patient an awareness of their overall eye health. Such an eye exam gives certain screenings to determine whether or not a patient is showing any signs of the early onset of eye diseases. This kind of eye exam also determines via a person's medical history. May 24, 2019 If you are allergic to hydroxychloroquine; any part of hydroxychloroquine; or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had. If you have had any eye changes or changes in eyesight due to hydroxychloroquine or drugs like this one. If you have psoriasis. If you have porphyria. If you are taking cimetidine. If you are taking any drugs that can cause a certain type of heartbeat that is not normal prolonged QT interval. Initially, central visual acuity may be unaffected, but the patient may notice related paracentral scotomas that often interfere with reading. The associated classic retinal toxicity is described as a bull’s eye maculopathy (ring of depigmented retinal pigment epithelium that spares the foveal area). Do you need a baseline eye exam before taking hydroxychloroquine Hydroxychloroquine Plaquenil Toxicity and Recommendations., What Is A Baseline Eye Exam? - EzineArticles Can you break plaquenil in halfSarcoidosis treatment usmle hydroxychloroquinePlaquenil lftsHydroxychloroquine monitoring ophthalmology Hydroxychloroquine is a relatively safe medication but it is recommended to have regular monitoring by an ophthalmologist eye doctor while taking this drug. Before you begin taking Plaquenil, tell you doctor your complete medical history including any eye problems that may have come from other aminoquinolines other antimalarial drugs such as chloroquine. Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus. Hydroxychloroquine Indications, Side Effects, Warnings.. The Risk of Retinal Toxicity with Plaquenil. It is recommended that you have an eye exam within the first year of use, then repeat every one to five years based on current guidelines. Tell Your Doctor Although there are few drug interactions with hydroxychloroquine, to be safe be sure to tell your doctor about all of the medications you are taking, including over-the-counter drugs and natural remedies. May 24, 2017 As I mentioned before, hydroxychloroquine eye toxicity is not reversible. Once it happens, it happens. So the trick is to catch it early. Fortunately, the changes occur VERY slowly. The American Academy of Ophthalmology recommends the following Obtain a baseline eye exam within the first year of starting hydroxychloroquine to document any complicating eye problem. Of course the aim is avoid drug related retinal toxicity, which on ophthalmic examination, appears as the classic Bull’s eye change affecting the macula. Once retinal toxicity from hydroxychloroquine occurs, it is thought that the retinal changes are permanent and the disease can progress even if hydroxychloroquine is stopped for 1 to 3 years.