My peripheral neuropathy actually went away too, and my rheumy thinks it was a rare, toxic side-effect of the Plaquenil. Get emergency medical help if you have any of these signs of an allergic reaction while taking hydroxychloroquine: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Fatigue is part of malaria, which is the normal use of this medication. Chloroquine expired side effects Hydroxychloroquine dosage lupus Hello, I thought fatigue is one of the symptoms of RA, so taking the right medication should help lessen fatigue, shouldn't it? When I was diagnosed with RA 2.5 years ago, I experienced fatigue and really bad pain on my foot, but since I started Plaquenil and Orencia 2 years ago, I have been in medically induced remission and don't have fatigue anymore. I took Plaquenil for Sjogren's Syndrome. It got so I couldn't walk up a curb without help before I switched to oral Methotrexate. My peripheral neuropathy actually went away too, and my rheumy thinks it was a rare, toxic side-effect of the Plaquenil. Immune system disorders Urticaria, angioedema, bronchospasm. PLAQUENIL has been shown to cause severe hypoglycemia including loss of consciousness that could be life threatening in patients treated with or without antidiabetic medications see DRUG INTERACTIONS and ADVERSE REACTIONS. Patients treated with PLAQUENIL should be warned about. This is not a complete list of side effects and others may occur. Call your doctor at once if you have a serious side effect such as:muscle weakness, twitching, or uncontrolled movement;loss of balance or coordination;blurred vision, light sensitivity, seeing halos around lights;pale skin, easy bruising or bleeding;confusion, unusual thoughts or behavior; orseizure (convulsions). Less serious side effects of hydroxychloroquine may include:headache, ringing in your ears, spinning sensation;nausea, vomiting, stomach pain;loss of appetite, weight loss;mood changes, feeling nervous or irritable;skin rash or itching; or hair loss. Will plaquenil help autoimmune urticaria Allergic reaction to plaquenil DailyStrength, Hydroxychloroquine - thigh muscle weakness? Is it ok to get flu shot while taking plaquenilBad side effects of plaquenilChloroquine resistance malaria cdcPlaquenil and prednisone during pregnancy Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Hydroxychloroquine Plaquenil. Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects.. Surprising Triggers of Chronic Hives Everyday Health. I can say, however, that I have not had any cross allergic reaction to other drugs sometimes associated with sulfa allergies. Whether you try Plaquenil or not is ultimately up to you and your doctor, but a lot will depend on the type and severity of reactions that you've had. Rashes are certainly a lot less severe than respiratory reactions. Selected from data included with permission and copyrighted by First Databank, Inc. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except. Home Autoimmune diseases Plaquenil Use in Autoimmune Diseases by Dermatologists and Rheumatologists. Plaquenil Use in Autoimmune Diseases by Dermatologists and Rheumatologists. I usually start with a low dose of 100-200 mg per day to help the patient adapt to the medicine and allow an increase in dose later to as high as 300-400 mg per day.