It is bioactivated hepatically to its primary metabolite, N-desethylamodiaquine, by the cytochrome p450 enzyme CYP2C8. Among amodiaquine users, several rare but serious side effects have been reported and linked to variants in the CYP2C8 alleles. C an u take plaquenil if u have an infection Does chloroquine affect birth control Plaquenil for autoimmune disorders How long for plaquenil to work Name Hydroxychloroquine sulfate Drug Entry Hydroxychloroquine. Hydroxychloroquine is a racemic mixture consisting of an R and S enantiomer. 2 Hydroxychloroquine is an aminoquinoline like chloroquine. 8 It is a commonly prescribed medication in the treatment of uncomplicated malaria, rheumatoid arthritis, chronic discoid lupus erythematosus, and systemic lupus erythematosus. 8. Structure, properties, spectra, suppliers and links for Chloroquine Phosphate, 1446-17-9. Name Chloroquine sulfate Drug Entry Chloroquine. Chloroquine is an aminoquinolone derivative first developed in the 1940s for the treatment of malaria. 4 It was the drug of choice to treat malaria until the development of newer antimalarials such as pyrimethamine, artemisinin, and mefloquine. 17 People who are poor metabolizers of amodiaquine display lower treatment efficacy against malaria, as well as increased toxicity. CYP2C8*1 is characterized as the wild-type allele, which shows an acceptable safety profile, while CYP2C8*2, *3 and *4 all show a range of "poor metabolizer" phenotypes. Chloroquine iupac name Chloroquine diphosphate salt, 98%, Acros Organics Fisher., Chloroquine Phosphate C18H29ClN3O4P ChemSpider Hydroxychloroquine brand name india Hydroxychloroquine has functional parent chloroquine chloroquine sulfate CHEBI50178 has part chloroquine R-chloroquine CHEBI48811 is a chloroquine S-chloroquine CHEBI39254 is a chloroquine Chloroquine CHEBI3638. Chloroquine sulfate - DrugBank. Chloroquine Oral Uses, Side Effects, Interactions, Pictures.. Identification Name Chloroquine Accession Number DB00608 APRD00468 Type Small Molecule Groups Approved, Investigational, Vet approved Description. Chloroquine is an aminoquinolone derivative first developed in the 1940s for the treatment of malaria. 4 It was the drug of choice to treat malaria until the development of newer antimalarials such as pyrimethamine, artemisinin, and mefloquine. 17 Chloroquine Sulfate is the sulfate salt of chloroquine, a quinoline compound with antimalarial and anti-inflammatory properties. Chloroquine is the most widely used drug against malaria, except for those cases caused by chloroquine resistant Plasmodium falciparum. Hydroxychloroquine is a derivative of chloroquine that has both antimalarial and antiinflammatory activities and is now most often used as an antirheumatologic agent in systemic lupus erythematosis and rheumatoid arthritis.