Please review the following URL and make sure that it is spelled correctly. Hydroxychloroquine belongs to a group of medications known as anti-inflammatories and antimalarials. Hydroxychloroquine long term side effects Chloroquine inhibit the novel heme polymerase enzyme Chloroquine hyperpigmentation pictures face Plaquenil pregnan Some of the medications you are taking for other medical conditions, such as high blood pressure or hormonal therapies, may adversely affect your lipid could inadvertently increase your triglycerides and "bad" LDL cholesterol while lowering your "good" HDL cholesterol. Blood tests If you take this medication for a long period of time, your doctor will likely want you to have blood tests to monitor your levels of red and white blood cells. Blood sugar levels Hydroxychloroquine may cause hypoglycemia low blood sugar levels. People with diabetes may find it necessary to monitor their blood sugar more frequently while using this medication. Blood Disorders. According to the New Zealand Dermatological Society, Plaquenil can cause abnormalities in blood counts. An abnormally low number of white blood cells can lead to infection, because white blood cells defend the body against bacteria. Low platelet count thrombocytopenia can lead to easy bleeding and bruising. It helps to reduce pain, stiffness, and swelling in joints. It is used alone or in combination with other anti-arthritic medications to treat rheumatoid arthritis. Does plaquenil raise your blood pressure Study Finds Blood Levels of Plaquenil may be Important Indicator of Eye., Plaquenil - Uses, Side Effects, Interactions. Chloroquine resistance treatmentHow long does chloroquine itching last Rarely, hydroxychloroquine can affect the bone marrow leading to reduced white blood cells leukopenia or platelets thrombocytopenia and abnormal red blood cells. Rare but potentially serious eye toxicity can occur. This toxicity affects a part of the eye called the retina and can lead to color blindness and even loss of vision. An. Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria. Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis.. Plaquenil - Uses, Side Effects, Interactions -. I suffer from low blood pressure when I stand up.oftentimes I feel very dizzy and faint and have to hold onto something to steady myself. I've mentioned it to my rheumy and he said it wasn't lupus related. Your doctor may gradually increase your dose. Once you have been taking the medication for a while and your condition has improved, your doctor may instruct you to lower your dose until you find the dose that works best with the fewest side this medication regularly in order to get the most benefit from it. Hi, Dizzyness, lightheaded, & balance issues can also be caused by lupus alone. Even if your mri comes back normal, the cause can still be from the lupus. The plaquenil may be adding to your dizzyness, but as the others said, you may want to split up the dose and possible you are on too high a dose.