Chloroquine has been extensively used in mass drug administrations, which may have contributed to the emergence and spread of resistance. It is recommended to check if chloroquine is still effective in the region prior to using it. Plaquenil arthritis medication Hydroxychloroquine for sjogren's syndrome vs another drug The mechanism of chloroquine and hydroxychloroquine toxicity is not well understood. Chloroquine has an affinity for pigmented melanin-containing structures, which may explain its toxic properties in the eye. Melanin serves as a free-radical stabilizer and can bind toxins, including retinotoxic drugs. List of causes of Chloroquine toxicity and Nerve symptoms, alternative diagnoses, rare causes, misdiagnoses, patient stories, and much more. Symptoms of a chloroquine overdose may include Drowsiness. Dizziness. Blurred vision. Fainting. Headache. Excessive excitability. Mood changes. Seizures. Irregular heartbeat. Slow, shallow breathing. Loss of consciousness. The Centers for Disease Control and Prevention recommend against treatment of malaria with chloroquine alone due to more effective combinations. In areas where resistance is present, other antimalarials, such as mefloquine or atovaquone, may be used instead. Chloroquine toxicity symptoms Chloroquine Side Effects Common, Severe, Long Term -, Chloroquine toxicity and Nerve symptoms - Symptom Checker. Is plaquenil used to treat fibromyalgiaMylan hydroxychloroquine highSide effects of plaquenil 200 mg tabletsCan you take birth control with plaquenilWhat happens if you take too much plaquenil An overdose of chloroquine can be fatal, especially in children. Chloroquine overdose must be treated quickly. You may be told to induce vomiting right away at home, before transport to an emergency room. Ask the poison control center how to induce vomiting in the case of an overdose. Chloroquine Uses, Side Effects, Dosage & Interactions. Chloroquine Aralen - Side Effects, Dosage, Interactions.. Hydroxychloroquine-Induced Retinal Toxicity - American Academy of.. List of causes of Chloroquine toxicity and Swelling symptoms, alternative diagnoses, rare causes, misdiagnoses, patient stories, and much more. Evidence of toxicity starts to become apparent within 1-2 hours of a toxic ingestion. The clinical features include Nonspecific effects — dizziness, nausea, vomiting Cardiovascular effects — rapid onset of hypotension, cardiac conduction defects, widened QRS and QT prolongation, broad complex tachycardias including torsades de pointes Chloroquine and hydroxychloroquine belong to the quinolone family. They are related drugs with similar clinical indications for use and similar manifestations of retinal toxicity, although their therapeutic and toxic doses differ.