But there also has to be something negative going on if it's making my hair fall out! mshistory - I know what you're saying is ALL true. I won't let things go to long like this, but I am hoping this is just some sort of rebound effect and that things will level off. I need to find a new one, but with 2 small kids and work full time, who has the time?! like i said i have super thick hair so i still have have a good amount but its def not super super thick like it once was. for those of you losing hair loss-lets be like Dolly Parton and all these other stars and wear wigs! It was making me feel better in other ways -no doubt. As for the psychologist, I did try that over the summer, but was not impressed by the one I was going to. If you remember, most wait at least 3 months before they even see any improvement. i lost a bunch of hair the 1st 4 months and now it has steadied off... along with the extreme dry patchy skin that bleads and all my lovely knew wrinkles along my eyes from doing warm compresses , massage and drops!!! this disease sure takes a toll52 yr old Sj S, APS w/strokes, Autonomic Neuropathy, PN, Nephrogenic DI, (CVID) Ig G def., Cushing's, Asthma, Gastroparesis. Is plaquenil an anti inflammatory Hydroxychloroquine 200 mg discounts Plaquenil and voice issues Hydroxychloroquine is a well-tolerated medication for various rheumatologic and dermatologic conditions. Its main side effects are gastrointestinal upset, skin rash, headache, and ocular toxicity1. Within the eye, hydroxychloroquine can adversely impact the cornea, ciliary body, and retina1 Commonly used on holidays in malaria prone destinations, chloroquine and hydroxychloroquine will not be over familiar to the emergency physician. However, it is one of the leading causes of drug overdose in malaria prone countries and also the occasional toddler has managed to consume the grandparents lupus or rheumatoid arthritis medication leading to lethal consequences. Hydroxychloroquine has an extremely long half life of around 32 days. This means that every 32 days, half of the previous amount of hydroxychloroquine in the body disappears. It takes around 5.5 half lives for a drug to be completely eliminated from your body meaning that you may need to wait for around 176 days. I thought methotrexate was stronger and had harder side effects??? Being 32 and feeling like I'm way too young to be dealing with any of this but trying to find my way through it BTW, seeing a psychiatrist and dealing with my depression and anxiety seriously saved my life. And your hair is growing back even while you're still on 200 a day? I wonder if what you're noticing is really the change in dose. You need to decided what is more important..or health.52 yr old Sj S, APS w/strokes, Autonomic Neuropathy, PN, Nephrogenic DI, (CVID) Ig G def., Cushing's, Asthma, Gastroparesis. Meds: IVIG & pre-meds, Arixtra, Aspirin, Plaquenil, Cardizem, Toprol XL, Domperidone, Nexium, Midodrine, Symbicort, Fentanyl, Percocet, Zofranthats the hard part---you never know.. If you feel really overwhelmed by all of this, it might be something to consider. now i still have quite a bit of hair but plaquenil made me lose a lot.. I'm wondering if 400 a day is just too much for some of us to handle? I say this because Plaquenil has a chemical half-life of 30-60 days (you can confirm this on wiki or RX info on the drug)--so it takes a LONG time to get out of your system..long for you to notice changes in days. whenever i take something new i think i get a weird side effect--but then again could it just be part of a flare...ughhhhh.. Hydroxychloroquine long half life Rx Side Effects New Plaquenil Guidelines and More., Chloroquine and Hydroxychloroquine - Life in the Fast Lane Chloroquine resistance mechanismDrug interactions between plaquenil mycophenolate and prednisone Given the long half-life of hydroxychloroquine and the previously documented within day variations of less than 8% this was considered appropriate. All patients in the cohort were prescribed hydroxychloroquine not to exceed a dose of 6.5 mg per kilogram. The maximum daily dose prescribed is 400 mg. Hydroxychloroquine Blood Levels in SLE Clarifying dosing.. How long does Hydroxychloroquine stay in your system?. Hydroxychloroquine - Wikipedia. Hydroxychloroquine oral tablet is used for short-term treatment of malaria, but it may be used for long-term treatment of lupus or rheumatoid arthritis. Hydroxychloroquine comes with risks if you. Hydroxychloroquine in whole blood. For further detailed information on long half-life drugs, please consult the Individual Product Bioequivalence Recommendation Guidance for Amiodarone HCl Tablets. Bioequivalence based on 90% CI Hydroxychloroquine. Waiver request of in-vivo testing A metabolite of chloroquine – hydroxychloroquine – has a long half-life 32–56 days in blood and a large volume of distribution 580–815 L/kg. The therapeutic, toxic and lethal ranges are usually considered to be 0.03 to 15 mg/l, 3.0 to 26 mg/l and 20 to 104 mg/l, respectively.