Although the disorder is rare, with a prevalence of one to 10 cases per million in adults and one to 3.2 cases per million in children, early recognition and treatment are important ways to decrease the morbidity of systemic complications. Dermatomyositis is an idiopathic inflammatory myopathy with characteristic skin manifestations. Effects of plaquenil on skin Side effects of plaquenil on eyes Plaquenil ocular testing For most people, there’s no cure for dermatomyositis. Treatment can improve the condition of your skin and muscle weakness. Available treatments include medication, physical therapy, and surgery. Hydroxychloroquine sulfate is frequently used to treat patients with dermatomyositis. It has been associated with an increased risk of adverse skin reactions in these patients. This study was performed to find out whether subsets of adult dermatomyositis patients, characterized by antibodies, are at increased risk for these skin eruptions. PLAQUENIL® HYDROXYCHLOROQUINE SULFATE TABLETS, USP DESCRIPTION PLAQUENIL h. ydroxychloroquine sulfate is a. white or practically white, crystalline. powder freely. soluble in water; practically insoluble in alcohol, chloroform, and in ether. The. chemical. name for. Poor prognostic indicators include poorly responsive disease, delay in diagnosis and the presence of malignancy. Patient management includes careful evaluation for underlying malignancy and liberal use of physical therapy, antihistamines, sunscreen and oral corticosteroids. Hydroxychloroquine for dermatomyositis Adverse Cutaneous Reactions to Hydroxychloroquine Are More., Dermatomyositis Autoantibodies associated with adverse. Chloroquine dormantChloroquine as antiinflammatoryCan glucose and bind to chloroquine Hydroxychloroquine sulfate Plaquenil Mechanism not understood; used in arthritis, lupus, malaria; can be used to reduce steroid dosage in myositis, particularly in children. Can treat muscle symptoms and dermatomyositis rash. Can cause damage to eyes’ retinas or corneas; regular eye exams needed. infusion of mixed immunoglobulins; IVIg Diseases - Dermatomyositis - Medical Management Muscular.. PLAQUENIL HYDROXYCHLOROQUINE SULFATE TABLETS, USP DESCRIPTION. Hydroxychloroquine alone insufficient to manage dermatomyositis. The reason hydroxychloroquine has been considered a ‘first-line’ therapy for cutaneous dermatomyositis for years is essentially because it is a ‘first-line’ therapy for skin disease in lupus,”. There's no cure for dermatomyositis, but treatment can improve your skin and your muscle strength and function. The earlier treatment is started in the course of dermatomyositis, the more effective it is. Medications. Medications used to treat dermatomyositis include Corticosteroids. Drugs such as prednisone can control dermatomyositis symptoms quickly. Hydroxychloroquine also known by its popular brand name Plaquenil is an oral medication that is commonly used to treat a variety of autoimmune diseases including systemic lupus, dermatomyositis, rheumatoid arthritis, Sjogren’s and many other conditions as well. In the field of hair loss, conditions such as lichen planopilaris, frontal fibrosing alopecia and discoid lupus are frequently treated with hydroxychloroquine.