Additionally, another exception occurred while executing the custom error page for the first exception. To my shock and surprise I was diagnosed with Lupus on Wed. Avn with hydroxychloroquine Should i take plaquenil in the morning or night If you're on steroids that can be whats causing you to gain weight. I can't offer any advice on losing the weight if you come off the Plaquenil. Like Joy said, Plaquenil is the first medication they use in treating lupus. It has the least amount of side effects and seems to work well for most patients. Some patients can not take the generic. Hence, if the loss of appetite and weight loss started after you started on this drug, then yes, it could be due to Plaquenil. However, if you had loss of appetite and weight loss before your started this drug, then the drug can aggravate the process. In this case, the cause of loss f appetite and weight loss has to be found. The maximum dose of Plaquenil is 6.5 mg/kg of ideal body weight per day, regardless of whether a person is overweight, underweight, or normal weight. One kilogram kg equals 2.2 pounds. Women with lupus who are OVER their ideal body weight should go by these dosing rules 5’ 7” or higher - up to 400 mg Plaquenil daily I have seen my rheumatologist for five years and I guess she just thought it was time. I am not shocked about having it just being diagnosed with it. Can plaquenil cause weight loss How good is Hydroxychloroquine, and any side effe. - HealthUnlocked, Plaquenil and loss of appetite - Lupus - MedHelp Plaquenil drug testGray nails and plaquenilHydroxychloroquine site mayoclinic.org Plaquenil caused a loss of appitite and weight loss for me. Both times I started taking it, the first time it was so serious I had to stop taking it. Started again several years later when I flared again and had loss of appitite and weight loss but a bit more moderate. Plaquenil & Weight Gain/Loss -. Protecting your eyesight when taking Plaquenil Lupus Foundation of.. Plaquenil Hydroxychloroquine - Side Effects, Dosage, Interactions - Drugs. Weight Loss. Weight loss that occurs during Plaquenil use is likely attributed to a lack of appetite and diarrhea. These two side-effects can account for a minor drop in weight loss. However, the severity of both side-effects will have an effect on how much weight loss occurs. Plaquenil can cause serious side effects when used in high doses for chronic diseases such as RA over the long term. The New Zealand Dermatological Society recommends that to decrease the risk of retina damage, no more than 200mg of Plaquenil should be taken a day, and a dose of 400mg per day should be taken no longer than a few weeks. I recently went on Plaquenil a few months ago, and I have been noticing how much weight I've been losing. I feel like I am losing too much weight. I am a thin person, and I am sick very often. Last week, I lost three pounds, and the week before I lost two pounds. Everyone keeps commenting that I'm.