The purpose of the blog is to help others live healthier, happier lives by sharing what has helped/ not helped in Carla's 20 years of having lupus (SLE). Humor has been one of the things that has consistently been helpful, and is incorporated fairly regularly into the posts. Losartan and hydroxychloroquine Plaquenil antacids The Use of Low-Dose Naltrexone for Lupus and Other Overlap Conditions WHAT IS LDN? Low-dose naltrexone or LDN is a medication that is getting more attention because of preliminary research showing promise for use with diseases like multiple sclerosis, some cancers, HIV/AIDS and other chronic pain conditions. Over the last several months, we, at Kaleidoscope I am looking to hear from anyone who has tried LDN low dose naltrexone for Sjogren's with success or failure. I am mostly interested in hearing about its impact on symptoms of dryness and glandular inflammation. I have seen a number of LDN related posts but very little follow up stories. I haven't heard of anyone getting worse while taking Low Dose Naltrexone. The most often reported side effects are sleep disturbances and vivid dreams, which most often go away after a short time. However, I understand that Plaquenil does have some devastating "side effects," including possible blindness! Patients also frequently experience symptoms of scalp itch, pain, and burning. Lichen planopilaris (LPP) is a variant of lichen planus that affects the scalp causing scarring hair loss. Low dose naltrexone and plaquenil Low Dose Naltrexone anyone? -, Low dose naltrexone stories for Sjogren's? Can you take plaquenil and cialis togetherPlaquenil for sjogren's reviewsTlr7 hydroxychloroquine ic50Are hydroxyzine and plaquenil the same thingPlaquenil and ankylosing spondylitis Overall, the patient noted significant clinical benefit with her fatigue and pain within two weeks of starting low-dose naltrexone but no significant change in her dry eyes or mouth. She continues to do well on low-dose naltrexone four months after stopping hydroxychloroquine due to the electrocardiogram EKG abnormalities. Sjogren's Syndrome Clinical Benefits of Low-dose Naltrexone.. Plaquenil & Low Dose Naltrexone -. Lupus Patient's Amazing Recovery with LDN LDNscience. Olive, I didn’t know much about low-dose naltrexone, so I looked it up. The wikipedia article isn’t a bad source for understanding this medication. I can see why tj was advising caution, as the article states that there have been many pseudoscientific claims about low-dose naltrexone without proper evidence from clinical trials. By Julie R October 4, 2016 at pm. Is anyone else taking low dose naltrexone for their rheumatoid disease? I’ll keep this short because I’ve tried to post on this topic before and my post didn’t “take”, wasn’t accepted, or whatever. Low-dose naltrexone LDN has been demonstrated to reduce symptom severity in conditions such as fibromyalgia, Crohn’s disease, multiple sclerosis, and complex regional pain syndrome. We review the evidence that LDN may operate as a novel anti-inflammatory agent in the central nervous system, via action on microglial cells.