It is a polymorphic ventricular tachycardia that exhibits distinct characteristics on the electrocardiogram (ECG). Symptoms and consequences include palpitations, dizziness, lightheadedness (during shorter episodes), fainting (during longer episodes), and sudden cardiac death. Torsades occurs as both an inherited (linked to at least 17 genes) Common causes for torsades de pointes include drug-induced QT prolongation and less often diarrhea, low serum magnesium, and low serum potassium or congenital long QT syndrome. North pharmaceuticals makers of hydroxychloroquine Prescription et surveillance du plaquenil au pdf How long before hydroxychloroquine starts working Torsade de pointes Introduction Quinine and chloroquine are the most common antimalarial drugs encountered in acute poisoning and can cause significant morbidity and mortality in overdose. Published December 2010. Publications Drug-induced QT prolongation and Torsades de Pointes - the facts. This article is more than five years old. Some content may no longer be current. A severe eye problem has happened with chloroquine. This may lead to lasting eyesight problems. The risk may be higher if you have some types of eye or kidney problems. The risk may also be higher with some doses of chloroquine, if you use chloroquine for longer than 5 years, or if you take certain other drugs like tamoxifen. Certain drugs and combinations of drugs resulting in drug interactions are common contributors to torsades de pointes risk. It can be seen in malnourished individuals and chronic alcoholics, due to a deficiency in potassium and/or magnesium. Chloroquine torsades Causes and management of torsades de pointes, Drug-induced QT prolongation and Torsades de Pointes - the. Chloroquine and hearing lossBiaxin and plaquenil for lymeChloroquine and hivPlaquenil herx symptoms Erythromycin is a macrolide antibiotic that is widely used for various infections of the upper respiratory tract, skin, and soft tissue. Similar to other macrolides clarithromycin, azithromycin, erythromycin has been linked to QTc interval prolongation and torsade de pointes TdP arrhythmia. Erythromycin, QTc interval prolongation, and torsade de.. Chloroquine Indications, Side Effects, Warnings -. Chloroquine Uses, Side Effects & Warnings -. Chloroquine Nivaquine was the first drug used for the treatment of malaria. It is effective against the blood stages of the malaria parasite and penetrates into most tissues. It is effective against Plasmodium ovale and malaria and susceptible strains of vivax and falciparum. Foscarnet has been associated with postmarketing reports of both QT prolongation and torsade de pointes TdP. Chloroquine administration is also associated with an increased risk of QT prolongation and TdP. If these drugs are administered together, obtain an electrocardiogram and electrolyte concentrations before and periodically during treatment. The most important thing to mention about the management of torsade de pointes is that there is essentially no evidence. The best available evidence is for the standard ACLS algorithm, with no differentiation made between torsades and standard monomorphic ventricular tachycardia.